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Severe apnoeas following immunisation in premature infants
  1. M H Slack,
  2. D Schapira
  1. Department of Paediatrics Royal Hampshire County Hospital Winchester Hampshire
  1. Dr M Slack.


Four premature infants developed apnoeas severe enough to warrant resuscitation after immunisation with diphtheria, pertussis, and tetanus (DPT), and Haemophilus influenzaeB (Hib). One required re-intubation and ventilation.

 Although apnoeas after immunisation are recognised, they are not well documented. It is time for further research to elucidate the best time to immunise such infants.

  • immunisations
  • apnoeas
  • prematurity

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