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The objectives of medical research
  1. M J R HEALY
  1. 23 Coleridge Court Milton Road
  2. Harpenden AL5 5LD

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    Editor—Dr Marlow’s interesting annotation on high frequency ventilation,1 with its pithy epigraph, adopts a common attitude to the methodology of medical research. This holds that, to be “scientific,” a study must specify a null hypothesis and then attempt, using data, to disprove it. This agrees with the writings of Karl Popper, but goes back further to the founding father of modern statistics, R A Fisher, who2 wrote: “Every experiment may …

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