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Early onset group B streptococcal neonatal infection in Oxford 1985-96
  1. Lahra M Mosesa,
  2. P T Heathb,
  3. A R Wilkinsonb,
  4. H E Jefferya,
  5. D Isaacsa,b
  1. aUniversity of Sydney, New South Wales, Australia, bDepartment of Paediatrics, John Radcliffe Hospital, Oxford OX3 9DU
  1. Dr Paul Heath. Email:paul.heath{at}


Of 74 920 babies live born in Oxford between 1985 and 1996, 41 (0.5 per 1000 95% CI 0.4–0.7) developed definite, culture confirmed, early onset (<48 hours) group B streptococcal infection and 32 (0.4 per 1000 95% CI 0.3–0.6) developed probable infection (sepsis plus colonisation). There was no significant variation in incidence with time. The mortality from definite infection was 19.5%, and from probable infection 6%.

 These data suggest that the incidence of group B streptococcal infection in Oxford is considerably lower than that reported in the USA.

  • group B streptococcal infection
  • sepsis
  • early onset
  • mortality

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