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Unusual course of neonatal hyperinsulinaemic hypoglycaemia (nesidioblastosis)
  1. ROLF BEHRENS,
  2. ANKE K PRENBE,
  3. HEIKE BÄRMEIER
  1. Children’s Hospital
  2. University of Erlangen-Nürnberg
  3. Loschgestr. I S.
  4. D-91054 Erlangen
  5. Germany

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    Editor—Neonatal hyperinsulinaemic hypoglycaemia (NHH) is characterised by hypoglycaemia, inadequate hyperinsulinism, a lack of urinary ketones, and requires instant and effective treatment to prevent cerebral damage. This consists of diazoxide, glucagon, and octreotide, a somatostatin analogue. None the less, most patients require subtotal pancreatectomy.

    We report the second child of a healthy family, who was delivered at 37 weeks after an uneventful pregnancy (birthweight 3430 g). Initially, hypoglycaemia (blood glucose of 80 mg/l) was noted. Table 1 summarises the most important laboratory values. The glucose:insulin ratio was …

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