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Dichorionic twins discordant for intrauterine growth retardation
  1. N J Sebire,
  2. C D’Ercole,
  3. K Hughes,
  4. J Rennie,
  5. K H Nicolaides
  1. Harris Birthright Research Centre for Fetal Medicine, Kings College Hospital, London SE5 8RX
  1. Professor KH Nicolaides.


A policy of expectant management until 32 weeks of gestation in 29 dichorionic pregnancies discordant for growth retardation resulted in an overall mortality of 24% (95% CI 13.9–37.2%) and a handicap of 2.2% (95% CI 0–12.0%). None of the normally grown co-twins died or was handicapped as a result of iatrogenic prematurity.

  • twins
  • dichorionic pregnancy
  • handicap
  • intrauterine growth retardation

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