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Erythromycin in neonatal postoperative intestinal dysmotility
  1. D E Simkiss,
  2. I P Adams,
  3. U Myrdal,
  4. I W Booth
  1. Children's Hospital, Birmingham
  2. East Birmingham Hospital, Birmingham
  3. Central Hospital, Vasteras, Sweden
  4. Institute of Child Health, University of Birmingham


    The motilin agonist erythromycin was used successfully in four infants receiving prolonged parenteral nutrition for severe intestinal dysmotility after gastrointestinal surgery. In a further child with a neuropathic intestinal pseudo-obstruction erythromycin induced a striking small intestinal manometric response, but was without effect in a child with an intestinal myopathy.

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