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Long bone radiographic abnormalities of congenital syphilis in a preterm infant
  1. Kirsten Tsan1,
  2. Brendan Mulcahy2,
  3. Atul Malhotra1,2
  1. 1 Department of Paediatrics, Monash University, Clayton, Victoria, Australia
  2. 2 Monash Children’s Hospital, Melbourne, Victoria, Australia
  1. Correspondence to Dr Atul Malhotra, Department of Paediatrics, Monash University, Clayton, VIC 3800, Australia; atul.malhotra{at}

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A preterm male infant was born at 29 weeks gestation to a mother with limited antenatal care (no early trimester serology). The mother presented in labour without signs of primary syphilis infection but had positive FTA-abs (fluorescent treponemal antibody absorption test) suggestive of latent syphilis. She received a single dose of penicillin prior to birth.

Mother was reactive to T-pallidum particle agglutination, FTA-abs IgM and chemiluminescence immunoassay with a rapid plasma reagin (RPR) of over 128. The infant was RPR and IgM reactive. Congenital syphilis was diagnosed …

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  • Contributors KT contributed to data collection and wrote the first manuscript draft. BM contributed to data collection and obtained patient consent. AM contributed to concept and data collection and is the guarantor. All authors edited and approved the final version of manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.