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Extreme preterm neonate with fetal warfarin syndrome
  1. Risa Birbal1,
  2. Olushola Olaniyi1,
  3. Paul Clarke1,2
  1. 1 Neonatal Intensive Care Unit, Norfolk and Norwich University Hospital NHS Foundation Trust, Norwich, Norfolk, UK
  2. 2 Norwich Medical School, University of East Anglia, Norwich, Norfolk, UK
  1. Correspondence to Dr Risa Birbal, Neonatal Intensive Care Unit, Norfolk and Norwich University Hospital NHS Foundation Trust, Norwich NR4 7UY, UK; risabirbal{at}gmail.com

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A 25+3 week gestation male infant weighing 493 g was delivered via caesarean section for intrauterine growth restriction and abnormal Dopplers. The mother was on long-term thromboprophylactic warfarin 5 mg/day due to her prosthetic mechanical heart valve following childhood rheumatic fever. Once pregnancy was diagnosed, at 4+0 weeks’ gestation, warfarin was discontinued and low-molecular-weight heparin was started. Warfarin was recommenced at 12+1 weeks’ gestation after a small maternal stroke.

Neonatal dysmorphic facial features …

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Footnotes

  • Twitter @risa_birbal

  • Contributors RB wrote the first manuscript draft. All authors contributed to manuscript revision and approved the final version.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; internally peer reviewed.