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Images in neonatal medicine
Congenital herpes simplex virus infection in a 26-week extremely premature infant
  1. Sota Iwatani,
  2. Dai Kataoka,
  3. Seiji Yoshimoto
  1. Neonatology, Hyogo Prefectural Kobe Children's Hospital, Kobe, Japan
  1. Correspondence to Dr Sota Iwatani, Neonatology, Hyogo Prefectural Kobe Children's Hospital, Kobe 650-0047, Japan; stiwatani_kch{at}

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At 26 weeks and 5 days of gestation, a 640 g male infant was born to a woman without a history of genital infection by vaginal delivery. In addition to respiratory distress, physical examination revealed marked general erythroderma without vesicles, especially on the face and thorax (figure 1). Initial laboratory evaluation demonstrated thrombocytopenia (13×109/L) and neutropenia (1.7×109/L), and antibiotic and antifungal treatments were administered for suspected sepsis. Over …

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  • Contributors SI drafted the initial manuscript. SI and DK treated the patient, and contributed to the acquisition of clinical data and imaging. SY supervised the manuscript. All authors approved the final manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; internally peer reviewed.