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CG and EM are joint first authors.
Twitter @cliodhna67, @HMactier
Contributors EM, HM and RH developed the concept of the paper. CG implemented the research with AB. RB, MS and SD analysed the data, and CG, EM, HM and RH drafted and critically reviewed the manuscript. All authors reviewed and agreed on the final manuscript.
Funding This study was funded by Glasgow Children's Hospital Charity.
Competing interests None declared.
Patient consent for publication Not required.
Ethics approval The study was approved by the local research ethics committee.
Provenance and peer review Not commissioned; externally peer reviewed.