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PHACE syndrome: importance of distinguishing infantile haemangioma from capillary malformation
  1. Hafsah Binti Sazali1,
  2. Nicholas Mark Allen2,
  3. Annette Murphy1
  1. 1 Department of Dermatology, Galway University Hospital, Galway, Ireland
  2. 2 Department of Paediatrics, National University of Ireland, Galway, Ireland
  1. Correspondence to Dr Hafsah Binti Sazali, Department of Dermatology, Galway University Hospital, Galway H91 YR71, Ireland; hafsahsazali{at}

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Two female neonates (Patient 1 and 2) were referred to dermatology with ‘capillary malformation’ (CM) and unilateral ‘orbital cellulitis’, respectively (figure 1A,C). Examination revealed bright red plaques on the eyelid and forehead, extending to the posterior scalp, neck, shoulder and chest in Patient 1, and the perioral area in Patient 2 (figure 1D). These were subtle red patches at birth but rapidly became more thickened in the ensuing weeks, causing …

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  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Parental/guardian consent obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.