Proton magnetic resonance spectroscopy lactate/N-acetylaspartate within 2 weeks of birth accurately predicts 2-year motor, cognitive and language outcomes in neonatal encephalopathy after therapeutic hypothermia

Subhabrata Mitra; Giles S Kendall; Alan Bainbridge; Magdalena Sokolska; Mary Dinan; Cristina Uria-Avellanal; David Price; Katie Mckinnon; Roxana Gunny; Angela Huertas-Ceballos; Xavier Golay; Nicola J Robertson

doi:10.1136/archdischild-2018-315478

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Original article

Proton magnetic resonance spectroscopy lactate/N-acetylaspartate within 2 weeks of birth accurately predicts 2-year motor, cognitive and language outcomes in neonatal encephalopathy after therapeutic hypothermia

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Subhabrata Mitra Institute for Women’s Health, University College London, London, UK PubMed articles Google scholar articles
Giles S Kendall Women and Children, University College London NHS Foundation Trust, London, UK PubMed articles Google scholar articles
Alan Bainbridge Medical Physics and Engineering, University College London NHS Foundation Trust, London, UK PubMed articles Google scholar articles
Magdalena Sokolska Medical Physics and Engineering, University College London NHS Foundation Trust, London, UK PubMed articles Google scholar articles
Mary Dinan Women and Children, University College London NHS Foundation Trust, London, UK PubMed articles Google scholar articles
Cristina Uria-Avellanal Institute for Women’s Health, University College London, London, UK PubMed articles Google scholar articles
David Price Medical Physics and Engineering, University College London NHS Foundation Trust, London, UK PubMed articles Google scholar articles
Katie Mckinnon Women and Children, University College London NHS Foundation Trust, London, UK PubMed articles Google scholar articles
Roxana Gunny Women and Children, University College London NHS Foundation Trust, London, UK PubMed articles Google scholar articles
Angela Huertas-Ceballos Women and Children, University College London NHS Foundation Trust, London, UK PubMed articles Google scholar articles
Xavier Golay Institute of Neurology, Queen Square, University College London, London, UK PubMed articles Google scholar articles
Nicola J Robertson Institute for Women’s Health, University College London, London, UK Division of Neonatology, Sidra Medicine, Doha, Qatar PubMed articles Google scholar articles

Correspondence to Professor Nicola J Robertson, Institute for Women’s Health, University College London, London WC1E 6HX, UK; n.robertson{at}ucl.ac.uk

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Citation

Mitra S, Kendall GS, Bainbridge A, et al

Archives of Disease in Childhood - Fetal and Neonatal Edition 2019;104:F424-F432.

Publication history

Received May 10, 2018
Revised August 13, 2018
Accepted September 7, 2018
First published October 15, 2018.

Online issue publication

June 19, 2019

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