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Dual-strain probiotics reduce NEC, mortality and neonatal bloodstream infections among extremely low birthweight infants
  1. Luisa Anna Denkel1,
  2. Frank Schwab1,
  3. Lars Garten2,
  4. Christine Geffers1,
  5. Petra Gastmeier1,
  6. Brar Piening1
  1. 1Institute of Hygiene and Environmental Medicine, Charité Universitätsmedizin Berlin, Berlin, Germany
  2. 2Department of Neonatology, Charité Universitätsmedizin Berlin, Berlin, Germany
  1. Correspondence to Dr Luisa Anna Denkel, Institute of Hygiene and Environmental Medicine, Charité Universitätsmedizin Berlin, German National Reference Center for the Surveillance of Nosocomial Infections, Berlin, 12203, Germany; luisa.denkel{at}

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Berrington and Ward Platt recently summarised current advances in the management of preterm infants born <1000 g, so-called extremely low birthweight (ELBW) infants.1 In this thoroughly done review, the authors highlighted the findings of the 2014 Cochrane review showing probiotics to reduce all-cause mortality and necrotizing enterocolitis (NEC) in preterm infants, but not in the subgroup of ELBW infants.2 …

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  • Contributors LAD, FS, CG, LG, BP, PG. Draft of initial manuscript: LAD. Neonatal expert: LG. Critical review of the manuscript: LAD, FS, LG, CG, PG, BP.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; internally peer reviewed.