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Using exhaled CO2 to guide initial respiratory support at birth: a randomised controlled trial
  1. Ashley Y Ngan1,
  2. Po-Yin Cheung1,2,
  3. Ann Hudson-Mason1,
  4. Megan O’Reilly1,2,
  5. Sylvia van Os1,
  6. Manoj Kumar2,
  7. Khalid Aziz1,2,
  8. Georg M Schmölzer1,2
  1. 1Centre for the Study of Asphyxia and Resuscitation, Neonatal Research Unit, Royal Alexandra Hospital, Edmonton, Alberta, Canada
  2. 2Division of Neonatology, Department of Pediatrics, University of Alberta, Edmonton, Canada
  1. Correspondence to Dr Georg M Schmölzer, Centre for theStudies of Asphyxia and Resuscitation, Neonatal ResearchUnit, Royal Alexandra Hospital, Edmonton, Alberta, T5H 3V9, Canada; georg.schmoelzer{at}me.com

Footnotes

  • Contributors GMS and AYN had full access to all the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis. Conception and design: GMS, KA, SvO, MOR, P-YC, MK. Collection and assembly of data: AYN, GMS, SvO, KA, AH-M, MOR, P-YC. Analysis and interpretation of the data: AYN, GMS, SvO, KA, AH-M, MOR, P-YC. Drafting of the article: AYN, GMS, KA, MOR, P-YC, SvO, AH-M. Critical revision of the article for important intellectual content: GMS, KA, MOR, AH-M, P-YC, SvO, AYN, MK. Final approval of the article: GMS, AYN, KA, MOR, P-YC, SvO, AH-M, MK.

  • Funding The study was supported by a Seed Funding Grant of the Department ofPediatrics, University of Alberta, Edmonton, Canada, and a Canadian RespiratoryHealth Professionals (CRHP) Grant, The Lung Association, Canada. MOR was supported by a Fellowship of the Molly Towell PerinatalFoundation. GMS is a recipient of the Heart and Stroke Foundation/University ofAlberta Professorship of Neonatal Resuscitation and a Heart and StrokeScholarship. No financial relationships with any organizations that might have aninterest in the submitted work in the previous 3 years; no other relationshipsor activities that could appear to have influenced the submitted work.

  • Competing interests None declared.

  • Patient consent Parental consent obtained.

  • Ethics approval The RAH Research Committee and Health Ethics Research Board, University of Alberta (Pro00034524).

  • Provenance and peer review Not commissioned; externally peer reviewed.

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Footnotes

  • Contributors GMS and AYN had full access to all the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis. Conception and design: GMS, KA, SvO, MOR, P-YC, MK. Collection and assembly of data: AYN, GMS, SvO, KA, AH-M, MOR, P-YC. Analysis and interpretation of the data: AYN, GMS, SvO, KA, AH-M, MOR, P-YC. Drafting of the article: AYN, GMS, KA, MOR, P-YC, SvO, AH-M. Critical revision of the article for important intellectual content: GMS, KA, MOR, AH-M, P-YC, SvO, AYN, MK. Final approval of the article: GMS, AYN, KA, MOR, P-YC, SvO, AH-M, MK.

  • Funding The study was supported by a Seed Funding Grant of the Department ofPediatrics, University of Alberta, Edmonton, Canada, and a Canadian RespiratoryHealth Professionals (CRHP) Grant, The Lung Association, Canada. MOR was supported by a Fellowship of the Molly Towell PerinatalFoundation. GMS is a recipient of the Heart and Stroke Foundation/University ofAlberta Professorship of Neonatal Resuscitation and a Heart and StrokeScholarship. No financial relationships with any organizations that might have aninterest in the submitted work in the previous 3 years; no other relationshipsor activities that could appear to have influenced the submitted work.

  • Competing interests None declared.

  • Patient consent Parental consent obtained.

  • Ethics approval The RAH Research Committee and Health Ethics Research Board, University of Alberta (Pro00034524).

  • Provenance and peer review Not commissioned; externally peer reviewed.

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