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Less invasive surfactant administration (LISA) in preterm infants with respiratory distress syndrome avoids mechanical ventilation and may further reduce the risk of death or bronchopulmonary dysplasia.1 A recent European survey indicates that the percentage of centres using LISA increased, but with wide variation in procedure. In particular, there is no consensus about whether sedation should be used.2 International guidelines recommend sedation for intubation but it can hamper spontaneous breathing, which is necessary for LISA. Recently, a study compared two groups …
Contributors All the authors contributed to the study.
CSD and MC collected the data and wrote the manuscript.
AE and IP participated in reviewing the manuscript.
CE contributed to the data collection.
TD designed the study and contributed to reviewing the manuscript.
Competing interests None declared.
Ethics approval French Committee of Evaluation for Protocol Research Observational (authorization no 2016-041).
Provenance and peer review Not commissioned; internally peer reviewed.
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