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Stoltz Sjöström et al 1 have demonstrated that higher intakes of energy, fat and carbohydrates, but not protein, were significantly associated with a lower risk of severe retinopathy of prematurity (ROP). Based on their current results and previous published studies, they propose a mechanism for the first phase of ROP pathogenesis. In this model, they suggest that a low-energy intake during the first 4 weeks of life can lead to arrested vascularisation. We commend the authors for this observation as well as for their comprehensive review of ROP pathogenesis.
However, although …
Contributors The author's responsibilities were as follows: SV designed the study and drafted the initial manuscript. GG is responsible for literature search and reviewed the scientific content of the manuscript.
Competing interests None declared.
Provenance and peer review Not commissioned; internally peer reviewed.