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A physiological approach to the timing of umbilical cord clamping at birth
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  • Published on:
    Oxygenation is not the only factor regulating heart rates at birth.
    • S.B. Hooper, Professor
    • Other Contributors:
      • G.R. Polglase and A.B. te Pas

    The alternative explanation for the cardiovascular differences between immediate and delayed cord clamping at birth suggested in this commentary is not new and has been acknowledged for over 50 years. The basic premise is that asphyxia is the underlying cause of birth-related bradycardias and that avoiding asphyxia will avoid the bradycardia and associated cardiac instability. However, neonatologists have known for almo...

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    Conflict of Interest:
    None declared.
  • Published on:
    Early cord clamping and stability of the circulatory transition during preterm birth

    The review by Hooper et al1 is timely and mounts a compelling case for a stable circulatory transition during preterm birth. However, advocacy of early ventilation with delayed cord clamping as the primary way forward to ensure such a transition is open to question, as the main supportive evidence for this paradigm comes from an experimental study by the same group,2 for which an alternative interpretation of observed f...

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    Conflict of Interest:
    None declared.