Download PDFPDF
NICE neonatal early onset sepsis guidance: greater consistency, but more investigations, and greater length of stay
Compose Response

Plain text

  • No HTML tags allowed.
  • Web page addresses and e-mail addresses turn into links automatically.
  • Lines and paragraphs break automatically.
Author Information
First or given name, e.g. 'Peter'.
Your last, or family, name, e.g. 'MacMoody'.
Your email address, e.g.
Your role and/or occupation, e.g. 'Orthopedic Surgeon'.
Your organization or institution (if applicable), e.g. 'Royal Free Hospital'.
Statement of Competing Interests


  • A rapid response is a moderated but not peer reviewed online response to a published article in a BMJ journal; it will not receive a DOI and will not be indexed unless it is also republished as a Letter, Correspondence or as other content. Find out more about rapid responses.
  • We intend to post all responses which are approved by the Editor, within 14 days (BMJ Journals) or 24 hours (The BMJ), however timeframes cannot be guaranteed. Responses must comply with our requirements and should contribute substantially to the topic, but it is at our absolute discretion whether we publish a response, and we reserve the right to edit or remove responses before and after publication and also republish some or all in other BMJ publications, including third party local editions in other countries and languages
  • Our requirements are stated in our rapid response terms and conditions and must be read. These include ensuring that: i) you do not include any illustrative content including tables and graphs, ii) you do not include any information that includes specifics about any patients,iii) you do not include any original data, unless it has already been published in a peer reviewed journal and you have included a reference, iv) your response is lawful, not defamatory, original and accurate, v) you declare any competing interests, vi) you understand that your name and other personal details set out in our rapid response terms and conditions will be published with any responses we publish and vii) you understand that once a response is published, we may continue to publish your response and/or edit or remove it in the future.
  • By submitting this rapid response you are agreeing to our terms and conditions for rapid responses and understand that your personal data will be processed in accordance with those terms and our privacy notice.
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.

Vertical Tabs

Other responses

  • Published on:
    Re: Impact of the NICE early onset neonatal sepsis guideline in our neonatal unit: Length of stay and number of lumbar punctures performed are not increased.
    • Arindam Mukherjee, Dr
    • Other Contributors:
      • Louise Davidson, Lazarus Anguvaa, Donovan Alistair Duffy and Nigel Kennea

    Mukherjee et al. were interested by the response to their paper indicating that not all units may have seen an increase in antibiotic use and length of stay following introduction of NICE guidance CG149. The important difference for our unit was the introduction of a second CRP at 18-24 hours to inform further investigations (lumbar puncture) and length of antibiotic course. It is not surprising that units that already u...

    Show More
    Conflict of Interest:
    None declared.
  • Published on:
    Impact of the NICE early onset neonatal sepsis guideline in our neonatal unit: Length of stay and number of lumbar punctures performed are not increased.
    • Jennifer Mitchell, Neonatal Grid Trainee
    • Other Contributors:
      • Jessica Burgess-Shannon, Andrew David Powls

    We were interested to read the experiences of other units 1-4 sharing their findings of increased duration of antibiotics, length of stay in hospital and lumbar punctures (LP) performed following implementation of the NICE guideline on prevention of early onset neonatal infection (EONI)5. We recently changed our practice to follow these NICE recommendations advocating observation of low risk infants to reduce antibiotic...

    Show More
    Conflict of Interest:
    None declared.