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4D phase contrast MRI in the preterm infant: visualisation of patent ductus arteriosus
  1. Kathryn M Broadhouse,
  2. Anthony N Price,
  3. Anna E Finnemore,
  4. David J Cox,
  5. A David Edwards,
  6. Joseph V Hajnal,
  7. Alan M Groves
  1. Division of Imaging Sciences & Biomedical Engineering, The Centre for the Developing Brain, King's College London, King's Health Partners, St. Thomas’ Hospital, London, UK
  1. Correspondence to Dr Kathryn M Broadhouse, Imaging Sciences & Biomedical Engineering Division, The Centre for the Developing Brain, 1st Floor South Wing, St Thomas’ Hospital, King's College, London SE1 7EH, UK; kathryn.broadouse{at}

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Persistently patent ductus arteriosus (PDA) is correlated with multiple adverse outcomes; however, whether this association is causal or casual remains unclear.1 Echocardiography offers high sensitivity for detection of PDA, but has limited ability to quantify flow within the duct and surrounding vessels. Consequently, the haemodynamic significance can only be inferred.2 Four-dimensional (4D) phase contrast MRI (PCMRI) allows visualisation and quantitative analysis of haemodynamics at almost any anatomical location throughout the cardiac cycle.3 Should …

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  • Funding Medical Research Center.

  • Competing interests KMB is funded by the Medical Research Council. JVH receives support from Philips Healthcare.

  • Patient consent Obtained.

  • Ethics approval The study was approved by the North West London Research Ethics Committee (06/Q0406/137).

  • Provenance and peer review Not commissioned; externally peer reviewed.