Mechanisms of the Development of Allergy (MeDALL): Introducing novel concepts in allergy phenotypes

JM Anto, J Bousquet, M Akdis, C Auffray, T Keil… - Journal of Allergy and …, 2017 - Elsevier
Asthma, rhinitis, and eczema are complex diseases with multiple genetic and environmental
factors interlinked through IgE-associated and non–IgE-associated mechanisms …

Use of induced sputum cell counts to investigate airway inflammation in asthma.

I Pin, PG Gibson, R Kolendowicz, A Girgis-Gabardo… - Thorax, 1992 - thorax.bmj.com
BACKGROUND: Airway inflammation is considered to be important in asthma but is
relatively inaccessible to study. Less invasive methods of obtaining sputum from patients …

Rhinitis and onset of asthma: a longitudinal population-based study

R Shaaban, M Zureik, D Soussan, C Neukirch… - The Lancet, 2008 - thelancet.com
Background A close relation between asthma and allergic rhinitis has been reported by
several epidemiological and clinical studies. However, the nature of this relation remains …

Understanding the complexity of IgE-related phenotypes from childhood to young adulthood: a Mechanisms of the Development of Allergy (MeDALL) seminar

JM Antó, M Pinart, M Akdis, C Auffray, C Bachert… - Journal of Allergy and …, 2012 - Elsevier
Mechanisms of the Development of Allergy (MeDALL), a Seventh Framework Program
European Union project, aims to generate novel knowledge on the mechanisms of initiation …

[HTML][HTML] Effect of 17q21 variants and smoking exposure in early-onset asthma

E Bouzigon, E Corda, H Aschard… - New England journal …, 2008 - Mass Medical Soc
Background A genomewide association study has shown an association between variants
at chromosome 17q21 and an increased risk of asthma. To elucidate the relationship …

Exposure to phthalates and phenols during pregnancy and offspring size at birth

C Philippat, M Mortamais, C Chevrier… - Environmental …, 2012 - ehp.niehs.nih.gov
Background: Data concerning the effects of prenatal exposures to phthalates and phenols
on fetal growth are limited in humans. Previous findings suggest possible effects of some …

Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function

MS Artigas, DW Loth, LV Wain, SA Gharib, M Obeidat… - Nature …, 2011 - nature.com
Pulmonary function measures reflect respiratory health and are used in the diagnosis of
chronic obstructive pulmonary disease. We tested genome-wide association with forced …

Adult lung function and long-term air pollution exposure. ESCAPE: a multicentre cohort study and meta-analysis

M Adam, T Schikowski, AE Carsin, Y Cai… - European respiratory …, 2015 - Eur Respiratory Soc
The chronic impact of ambient air pollutants on lung function in adults is not fully understood.
The objective of this study was to investigate the association of long-term exposure to …

Identifying adult asthma phenotypes using a clustering approach

V Siroux, X Basagaña, A Boudier, I Pin… - European …, 2011 - Eur Respiratory Soc
There is a need to improve asthma characterisation by integrating multiple aspects of the
disease. The aim of the present study was to identify distinct asthma phenotypes by applying …

Asthma control in Europe: a real-world evaluation based on an international population-based study

L Cazzoletti, A Marcon, C Janson, A Corsico… - Journal of allergy and …, 2007 - Elsevier
BACKGROUND: Epidemiologic evidence related to asthma control in patients from the
general population is scanty. OBJECTIVES: We sought to assess asthma control in several …