Latest advances in understanding preeclampsia

CW Redman, IL Sargent - Science, 2005 - science.org
Preeclampsia is a relatively common pregnancy disorder that originates in the placenta and
causes variable maternal and fetal problems. In the worst cases, it may threaten the survival …

Pre-eclampsia: pathophysiology and clinical implications

GJ Burton, CW Redman, JM Roberts, A Moffett - Bmj, 2019 - bmj.com
Pre-eclampsia is a common disorder that particularly affects first pregnancies. The clinical
presentation is highly variable but hypertension and proteinuria are usually seen. These …

The long-term outcome in surviving infants with Apgar zero at 10 minutes: a systematic review of the literature and hospital-based cohort

DJ Harrington, CW Redman, M Moulden… - American journal of …, 2007 - Elsevier
OBJECTIVE: The purpose of this study was to investigate the outcomes of infants who had
Apgar scores of zero at 10 minutes and were resuscitated successfully. STUDY DESIGN …

Systemic inflammatory priming in normal pregnancy and preeclampsia: the role of circulating syncytiotrophoblast microparticles

SJ Germain, GP Sacks, SR Soorana… - The Journal of …, 2007 - journals.aai.org
Systemic inflammatory responsiveness was studied in normal human pregnancy and its
specific inflammatory disorder, pre-eclampsia. Compared with nonpregnancy, monocytes …

IFPA Senior Award Lecture: making sense of pre-eclampsia–two placental causes of preeclampsia?

CW Redman, IL Sargent, AC Staff - Placenta, 2014 - Elsevier
Incomplete spiral artery remodelling is the first of two stages of pre-eclampsia, typically of
early onset. The second stage comprises dysregulated uteroplacental perfusion and …

Evidence for a novel HLA antigen found on human extravillous trophoblast and a choriocarcinoma cell line.

SA Ellis, IL Sargent, CW Redman, AJ McMichael - Immunology, 1986 - ncbi.nlm.nih.gov
We describe the characterization of a novel HLA Class I molecule, which we have isolated
from chorionic cytotrophoblast cell membranes, and from a trophoblast-derived …

Early platelet consumption in pre-eclampsia.

CW Redman, J Bonnar, LJ Beilin - Br Med J, 1978 - bmj.com
One hundred and thirty-one women with chronic hypertension were studied serially during
pregnancy to determine the sequence of events in the development of superimposed pre …

Cell populations in human early pregnancy decidua: characterization and isolation of large granular lymphocytes by flow cytometry.

PM Starkey, IL Sargent, CW Redman - Immunology, 1988 - ncbi.nlm.nih.gov
Cell populations of human pregnancy decidua, obtained by enzymic digestion from first
trimester samples, were analysed by flow cytometry after labelling with monoclonal …

[HTML][HTML] Characterisation of syncytiotrophoblast vesicles in normal pregnancy and pre-eclampsia: expression of Flt-1 and endoglin

DS Tannetta, RA Dragovic, C Gardiner, CW Redman… - PloS one, 2013 - journals.plos.org
Background The placental syncytiotrophoblast releases micro and nanovesicles (STBM),
into the maternal circulation in normal pregnancy and in increased amounts in pre …

Strategy for standardization of preeclampsia research study design

L Myatt, CW Redman, AC Staff, S Hansson… - …, 2014 - Am Heart Assoc
Preeclampsia remains a major problem worldwide for mothers and babies. Despite
intensive study, we have not been able to improve the management or early recognition of …