Five randomized controlled trials comparing lower (85-89%) versus higher (91-95%) pulse
oximeter saturation (SpO2) targets for extremely preterm infants have now been reported …

Objective CHF5633 (Chiesi Farmaceutici SpA, Parma, Italy) is the first fully synthetic
surfactant enriched by peptide analogues of two human surfactant proteins. We planned to …

Purpose To investigate whether the observed international differences in retinopathy of
prematurity (ROP) treatment rates within the Benefits of Oxygen Saturation Targeting …

Background A pretrial clinical improvement project for the BOOST-II UK trial of oxygen
saturation targeting revealed an artefact affecting saturation profiles obtained from the …

Purpose We tested the ability of the 'Weight, IGF-1, Neonatal Retinopathy of Prematurity
(WINROP)'clinical algorithm to detect preterm infants at risk of severe Retinopathy of …

Background The acid-base status of infants around birth can provide information about their
past, current and future condition. Although umbilical cord blood pH< 7.0 or base deficit≥ 12 …

Objective To evaluate the effect of implementing automated oxygen control as routine care
in maintaining oxygen saturation (SpO 2) within target range in preterm infants. Methods …

Retinopathy of prematurity (ROP) was first observed soon after the widespread introduction
of oxygen therapy into neonatal care. Early trials suggested that restricting oxygen …

When Joseph Priestly first described oxygen more than 200 years ago he raised caution
about possible toxicity, commenting that, if breathed by a healthy person, it may cause them …

Background: Oxygen saturation (Spo2) monitors are commonly used to determine the need
for supplemental oxygen. We aimed to describe the range of arterial oxygen tensions (Pao2) …