Dietary interventions for recurrent abdominal pain (RAP) and irritable bowel syndrome (IBS) in childhood

AA Huertas‐Ceballos, S Logan… - Cochrane database …, 2008 - cochranelibrary.com
Background Between 4% and 25% of school‐age children complain of recurrent abdominal
pain (RAP) of sufficient severity to interfere with daily activities. It is unclear whether the …

Ethics and social acceptability of a proposed clinical trial using maternal gene therapy to treat severe early‐onset fetal growth restriction

M Sheppard, RN Spencer, R Ashcroft… - … in Obstetrics & …, 2016 - Wiley Online Library
Objective To evaluate the ethical and social acceptability of a proposed clinical trial using
maternal uterine artery vascular endothelial growth factor (VEGF) gene therapy to treat …

[HTML][HTML] EVERREST prospective study: a 6-year prospective study to define the clinical and biological characteristics of pregnancies affected by severe early onset …

R Spencer, G Ambler, J Brodszki, A Diemert… - BMC pregnancy and …, 2017 - Springer
Background Fetal growth restriction (FGR) is a serious obstetric condition for which there is
currently no treatment. The EVERREST Prospective Study has been designed to …

Proton magnetic resonance spectroscopy lactate/N-acetylaspartate within 2 weeks of birth accurately predicts 2-year motor, cognitive and language outcomes in …

S Mitra, GS Kendall, A Bainbridge, M Sokolska… - Archives of Disease in …, 2019 - fn.bmj.com
Objective Brain proton (1 H) magnetic resonance spectroscopy (MRS) lactate/N-
acetylaspartate (Lac/NAA) peak area ratio is used for prognostication in neonatal …

Evaluation of early childhood social-communication difficulties in children born preterm using the Quantitative Checklist for Autism in Toddlers

HS Wong, A Huertas-Ceballos, FM Cowan… - The Journal of …, 2014 - Elsevier
Objectives To characterize early childhood social-communication skills and autistic traits in
children born very preterm using the Quantitative Checklist for Autism in Toddlers (Q-CHAT) …

[PDF][PDF] Maternal PlGF and umbilical Dopplers predict pregnancy outcomes at diagnosis of early-onset fetal growth restriction

R Spencer, K Maksym, K Hecher… - Journal of Clinical …, 2023 - Am Soc Clin Investig
BACKGROUND Severe, early-onset fetal growth restriction (FGR) causes significant fetal
and neonatal mortality and morbidity. Predicting the outcome of affected pregnancies at the …

White matter NAA/Cho and Cho/Cr ratios at MR spectroscopy are predictive of motor outcome in preterm infants

GS Kendall, A Melbourne, S Johnson, D Price… - Radiology, 2014 - pubs.rsna.org
Purpose To determine (a) whether diffuse white matter injury of prematurity is associated
with an increased choline (Cho)–to-creatine (Cr) ratio and a reduced N-acetylaspartate …

Pressure passivity of cerebral mitochondrial metabolism is associated with poor outcome following perinatal hypoxic ischemic brain injury

S Mitra, G Bale, D Highton, R Gunny… - Journal of Cerebral …, 2019 - journals.sagepub.com
Hypoxic ischemic encephalopathy (HIE) leads to significant morbidity and mortality.
Impaired autoregulation after hypoxia-ischaemia has been suggested to contribute further to …

[HTML][HTML] Prognostic value of neonatal EEG following therapeutic hypothermia in survivors of hypoxic-ischemic encephalopathy

T Koskela, GS Kendall, S Memon, M Sokolska… - Clinical …, 2021 - Elsevier
Objective Early prediction of neurological deficits following neonatal hypoxic-ischemic
encephalopathy (HIE) may help to target support. Neonatal animal models suggest that …

[HTML][HTML] How to use abdominal X-rays in preterm infants suspected of developing necrotising enterocolitis

R Soni, A Katana, JI Curry, PD Humphries… - Archives of Disease in …, 2020 - ep.bmj.com
Necrotising enterocolitis (NEC) in preterm babies is a serious gastrointestinal emergency
with potentially devastating consequences. Prompt and accurate diagnosis continues to be …