IgG4 deficiency with Rothmund-Thomson syndrome: a case report

M Kubota; M Yasunaga; H Hashimoto; H Kimata; H Mikawa; A Shinya; C Nishigori

doi:10.1007/BF01955898

IgG4 deficiency with Rothmund-Thomson syndrome: a case report

Eur J Pediatr. 1993 May;152(5):406-8. doi: 10.1007/BF01955898.

Authors

M Kubota¹, M Yasunaga, H Hashimoto, H Kimata, H Mikawa, A Shinya, C Nishigori

Affiliation

¹ Department of Paediatrics, Kyoto University, Japan.

PMID: 8319706
DOI: 10.1007/BF01955898

Abstract

We describe a patient with Rothmund-Thomson syndrome and IgG4 deficiency. In vitro examination of his peripheral mononuclear cells revealed impaired IgG4 synthesis. Susceptibility to sinus and pulmonary infections was cured by monthly immunoglobulin infusions.

Publication types

Case Reports

MeSH terms

Child, Preschool
Humans
IgG Deficiency / complications*
IgG Deficiency / immunology
Immunoglobulin G / biosynthesis
Immunoglobulin G / blood
Leukocytes, Mononuclear
Male
Rothmund-Thomson Syndrome / complications*
Rothmund-Thomson Syndrome / immunology

Substances

Immunoglobulin G