Neurotrophins. Keeping track of changing neurotrophic theory

Curr Biol. 1994 Jul 1;4(7):662-5. doi: 10.1016/s0960-9822(00)00149-4.

Abstract

The requirement for neurotrophins in the development of specific neuronal populations is endorsed by transgenic mice lacking neurotrophin receptors, but central nervous regions of the mice are paradoxically unaffected.

Publication types

  • Review

MeSH terms

  • Animals
  • Apoptosis / physiology
  • Central Nervous System / abnormalities
  • Central Nervous System / cytology
  • Central Nervous System / embryology
  • Central Nervous System / physiology
  • Embryonic and Fetal Development / genetics
  • Genes
  • Genes, Lethal
  • Mice
  • Mice, Knockout
  • Mice, Neurologic Mutants / anatomy & histology
  • Mice, Neurologic Mutants / genetics
  • Mice, Transgenic
  • Models, Molecular
  • Models, Neurological*
  • Nerve Growth Factors / physiology*
  • Neuronal Plasticity
  • Phenotype
  • Receptors, Nerve Growth Factor / chemistry
  • Receptors, Nerve Growth Factor / genetics
  • Receptors, Nerve Growth Factor / physiology*

Substances

  • Nerve Growth Factors
  • Receptors, Nerve Growth Factor