Maternal smoking and respiratory distress syndrome

Am J Obstet Gynecol. 1983 Oct 15;147(4):446-50. doi: 10.1016/s0002-9378(16)32242-6.

Abstract

Infants of 603 patients on whom information about smoking habits during pregnancy was available were studied for incidence respiratory distress syndrome. Among the 360 patients who did not smoke, the incidence of respiratory distress syndrome in the neonate was 15.1%, whereas among patients who smoked, the incidence was 9.1%. We speculate that smoking produces a condition of chronic stress in the fetus which brings about an acceleration of fetal pulmonary maturation.

PIP: Infants of 603 patients on whom information about smoking habits during pregnancy was available were studied for incidence of respiratory distress syndrome (RDS). Among the 360 patients who did not smoke, the incidence of RDS in the neonate was 15.1%, whereas among patients who smoked, the incidence was 9.1%. We speculate that smoking produces a condition of chronic stress in the fetus which in turn brings about an acceleration of fetal pulmonary maturation.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Amniocentesis
  • Birth Weight
  • Female
  • Humans
  • Infant, Newborn
  • Male
  • Phosphatidylcholines / analysis
  • Pregnancy*
  • Respiratory Distress Syndrome, Newborn / epidemiology*
  • Risk
  • Smoking*
  • Sphingomyelins / analysis

Substances

  • Phosphatidylcholines
  • Sphingomyelins