Has advice on periconceptional folate supplementation reduced neural-tube defects?

Lancet. 1999 Sep 18;354(9183):998-9. doi: 10.1016/S0140-6736(99)03248-1.

Abstract

Periconceptional folate supplementation has been encouraged in the UK since the early 1990s, but no concurrent decline in neural-tube-defect pregnancies has been observed by regional congenital anomaly registers.

Publication types

  • Letter

MeSH terms

  • Female
  • Folic Acid / therapeutic use*
  • Health Education
  • Humans
  • Infant, Newborn
  • Neural Tube Defects / epidemiology
  • Neural Tube Defects / prevention & control*
  • Preconception Care
  • Pregnancy
  • Registries / statistics & numerical data
  • United Kingdom / epidemiology

Substances

  • Folic Acid