Frequency and timing of recurrent events in infants using home cardiorespiratory monitors,☆☆,,★★

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Abstract

Objective: To determine the incidence, type, timing, and factors predictive of recurrent significant events in infants with home cardiorespiratory monitors. Study design: We reviewed data accumulated for 147 patients with an event-recorder type of monitor. The infants were allocated to one of four diagnostic categories: apparent life-threatening events (ALTE, n = 73), former premature infants with persistent apnea and bradycardia (n = 29), siblings of victims of sudden infant death syndrome (SIDS) (n = 24), and parental anxiety after a nonsignificant event (n = 21). Results: Compliance with monitoring was excellent; the monitors were used on 94% of the prescribed days. Fifty-three (36%) of 147 infants had significant events; of those, 46 (87%) experienced their first event during the first month of monitoring, and 69% of the events occurred during that first month. The most prevalent event type was a bradycardic event. Among infants in the ALTE group, events during the initial investigation period predicted the likelihood of events at home; 2 of the 47 infants (4%) with negative results for an investigation and no events recorded in hospital had apnea, and 4 had a bradycardic event (9%). In contrast, when significant events were recorded in hospital, the events were likely to recur at home (69% and 35% of the infants had apnea or bradycardia, respectively; p < 0.001). Conclusion: Because most apnea, bradycardia, and recurrent clinical events began during the first month of monitoring, we emphasize the need for vigilant follow-up care of infants immediately after institution of home monitoring. Readmission for investigation is warranted in infants with severe or multiple recurrent events. (J Pediatr 1998;312:783-9)

Section snippets

METHODS

We reviewed the records of all infants followed up in the Apnea Clinic at the Montreal Children's Hospital between September 1990 and December 1995. Three groups judged to be at increased risk for SIDS were defined: (1) Infants with apparent life-threatening events were defined according to the National Institutes of Health (NIH) Consensus Statement on Apnea of Infancy.8 They had received vigorous and prolonged stimulation, and sometimes mouth-to-mouth respiration and cardiac massage to

RESULTS

Between September 1990 and December 1995, 193 infants were discharged home with a monitor. An additional 9 infants (all siblings of children who had died of SIDS) were followed up, although the parents did not use a home monitor at any time. Of the 193 infants, 46 had a nonrecording monitor for either some part of or the whole recording period (14 ALTE, 30 SIDS siblings, 1 former premature infant, and 1 parental anxiety infant). These infants were followed up at a time when we had insufficient

DISCUSSION

The current study provides information on the natural history of apnea and bradycardia occurring in infants undergoing surveillance at home with cardiorespiratory monitors. In our study, subsequent significant events were recorded in 36% of these infants. The probability of having recurrent significant events at home was related to three factors. First, former premature infants were more likely to have events than infants with ALTE, SIDS siblings, or infants monitored for parental anxiety.

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From the Jeremy Rill Center for SIDS and Respiratory Control Disorders, the Divisions of Respiratory and Newborn Medicine, Department of Pediatrics, and the Nursing Department, McGill University, Montreal Children's Hospital, Quebec, Canada.

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A. C. is a Research Scholar (Chercheur-Boursier) of the Fonds de la recherche en santé du Québec and an Associate Professor of Pediatrics, McGill University.

Reprint requests: Aurore Côté, MD, Division of Respiratory Medicine, Montreal Children's Hospital, 2300 rue Tupper, Montréal, Canada H3H 1P3.

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