Vitamin K in infancy

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  • Cited by (211)

    • Vitamin K in human health and metabolism: A nutri-genomics review

      2022, Trends in Food Science and Technology
      Citation Excerpt :

      Poor VK carriage through placenta, low content of VK1 in breast milk, and liver immaturity leads to inefficient use of VK and recycling represent part of the conditions further leads to a situation known as VK deficiency bleeding (VKDB) (American Academy of Pediatrics Committee on Fetus and Newborn, 2003; Pichler & Pichler, 2008)⁠. There are three types of VKDB as follows: early-onset (occurs within the first 24 h after birth), classic (occurs within 2–7 days), and late-onset (occurs between 2 and 12 weeks and up to 6 months) (Lane & Hathaway, 1985). Early-onset VKDB or Early haemorrhagic disease of the newborn (Early HDN) is commonly associated with maternal malabsorption disorders and medications that inhibit the activity of VK, such as antiepileptics (carbamazepine, phenytoin, and barbiturates), anti-tuberculosis medications (isoniazid and rifampicin), certain antibiotics (cephalosporins), and VK antagonists (Warfarin/Coumadin).

    • Intracranial Hemorrhage

      2018, Volpe's Neurology of the Newborn
    View all citing articles on Scopus

    Supported in part by Grant 2794-7 from the Thrasher Research Fund.

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