Cranial blood volume changes during mechanical ventilation and spontaneous breathing in newborn infants

doi:10.1016/S0022-3476(82)80026-7

The Journal of Pediatrics

Volume 101, Issue 6, December 1982, Pages 984-987

https://doi.org/10.1016/S0022-3476(82)80026-7 Get rights and content

We devised a noninvasive method to compare changes in cranial blood volume during mechanical ventilation with changes occurring during spontaneous breathing in newborn infants. In ten infants receiving mechanical ventilation, cranial blood volume increased during inspiration by a mean of 8.3%. We found a consistent relationship between clinical estimation of lung compliance and the amount of cranial volume expansion. During spontaneous breathing in ten infants cranial blood volume decreased during inspiration by a mean of 5.8%. The findings indicate the need for careful monitoring during periods of rapid changes in lung compliance.

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Supported by the Children's Hospital of Winnipeg Research Foundation, Inc.

Presented in part at the Society for Pediatric Research Meeting, San Antonio, Texas, May, 1980.

View full text

Cranial blood volume changes during mechanical ventilation and spontaneous breathing in newborn infants†

Clin Perinatol

J Pediatr

Clin Perinatol

Clin Perinatal

Cerebral intraventricular haemorrhage and subependymal matrix infarction in the fetus and premature newborn

Am J Pathol

Hemorrhagies cerebrales, intraventricularires chez le premature. I. Anatomie et physiopathologie

Biol Neonate

Distribution of the terminal hemorrhages in the brain wall in stillborn preterm and non-viable neonates

Subependymal cerebral hemorrhage in infancy

Am J Dis Child

Effect of CO2 and 100% O2 on cerebral blood flow in preterm infants

J Appl Physiol

A quantitative non-invasive method to measure cerebral blood flow in newborn infants

Pediatrics