Failure of daily lumbar punctures to prevent the development of hydrocephalus following intraventricular hemorrhage**
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Cited by (71)
Management of Post-hemorrhagic Ventricular Dilatation in the Infant Born Preterm
2020, Journal of PediatricsSurgical management of intraventricular hemorrhage and posthemorrhagic hydrocephalus in premature infants
2020, Biomedical JournalCitation Excerpt :It has been suggested that daily LPs need to occur for at least 7 days to be effective whereas the repeated procedures can be traumatic for the premature infants and, therefore, not always the preferred treatment. Randomized controlled trials have failed to demonstrate a significant effect of serial LPs on the rates of morbidity, mortality or conversion to permanent VP shunt in the treatment of PHH [13–16]. Lumbar tappings are also associated with increased risk of CSF infection [17].
Preterm Intraventricular Hemorrhage/Posthemorrhagic Hydrocephalus
2018, Volpe's Neurology of the NewbornPathogenesis of Germinal Matrix Hemorrhage
2017, Fetal and Neonatal Physiology, 2-Volume SetIntraventricular Hemorrhage in the Neonate
2011, Fetal and Neonatal Physiology E-Book, Fourth EditionIntracranial Hemorrhage in the Preterm Infant: Understanding It, Preventing It
2009, Clinics in PerinatologyCitation Excerpt :It is also frequently difficult to clearly delineate between a frank hydrocephalic process and an atrophic nonprogressive ventricular dilatation because they often coexist. Moreover, in clinical trials early (before the onset of PHH) serial lumbar punctures were used unsuccessfully to prevent the evolution of GM-IVH to PHH.158 Early intrathecal fibrinolytic therapy (urokinase, tissue plasminogen activator) also failed to prevent hydrocephalus that required shunting.133
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Supported by the Allen P. and Joseph B. Green Foundation, and by National Foundation grant No. 6-174.