Syndrome of inappropriate antidiuretic hormone secretion in neonates with pneumothorax or atelectasis

doi:10.1016/S0022-3476(77)81325-5

The Journal of Pediatrics

Volume 91, Issue 3, September 1977, Pages 459-463

https://doi.org/10.1016/S0022-3476(77)81325-5 Get rights and content

Nine episodes of the syndrome of inappropriate antidiuretic hormone secretion occurred in five newborn infants following atelectasis or pneumothorax. All infants had pre-existing lung disease and were being treated with positive pressure ventilation. The mean interval between acute atelectasis or penumothorax and the development of diagnostic hyponatremia, hypo-osmolal serum, hyperosmolal urine, and oliguria was 13.4 hours. Fluid restriction and removal of the triggering event resulted in resolution of the abnormalities within 1.5 to 4 days. Infants who develop atelectasis or pneumothorax should be evaluated for the subsequent occurrence of SIADH; the administration of a water load to them may result in dilutional hyponatremia, for which fluid restriction, not sodium infusion, is the proper therapy.

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Syndrome of inappropriate antidiuretic hormone secretion in neonates with pneumothorax or atelectasis

J Pediatr

J Biol Chem

Am J Med

Am J Med

Am J Med

Am J Med

Studies on the mechanism of a sodium-losing syndrome in two patients with mediastinal tumors

J Clin Invest

Hyponatremia following asphyxia neonatorum

Acta Paediatr Scand

Inappropriate antidiuretic hormone secretion in a neonate with meningitis

Am J Dis Child

Inappropriate antidiuretic hormone secretion in an infant with severe pneumonia

Am J Dis Child

Urinary flow rates and urea excretion rates in newborn infants

Biol Neonate

Water metabolism

Antidiuretic hormone and the factors which determine its release

Acute reduction in extracellular fluid volume and the concentration of antidiuretic hormone in blood

Endocrinology

Renal hemodynamics and antidiuretic hormone release associated with volume regulation

Am J Physiol

Vasopressin in blood: Effect of hemorrhage

Endocrinology

Release of vasopressin during hypoxia

J Physiol Lond