Massive intracerebellar hemorrhage in low-birth-weight infants
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Cited by (75)
Cerebral palsy after very preterm birth - an imaging perspective
2020, Seminars in Fetal and Neonatal MedicineThe developing brain by trimester
2020, Handbook of Clinical NeurologyFetal and neonatal neuroimaging
2019, Handbook of Clinical NeurologyCitation Excerpt :Cerebellar hemorrhages may range from small unilateral lesions, to large or bilateral hemorrhages that may be associated with tissue infarction. Morbidity is high for infants with large supratentorial and cerebellar hemorrhages (Martin et al., 1976; Perlman et al., 1983) and cerebellar hemorrhages have been associated with an increased risk of abnormalities on neurologic examination (Dyet et al., 2006; Tam et al., 2011) (Fig. 4.17). Although not common, perinatal arterial ischemic stroke (PAIS) occurs more often in the neonatal period than at any other time in childhood (Nelson, 2007; Raju et al., 2007).
Cerebellar hypoplasia of prematurity: Causes and consequences
2019, Handbook of Clinical NeurologyCitation Excerpt :Further research is needed to understand how the location, depth, and topological extent of cerebellar injury give rise to specific patterns of neurodevelopmental impairments, particularly for the punctate lesions. Motor outcome in preterm infants with cerebellar hemorrhage is more likely to be impaired compared to preterm infants without cerebellar injury, particularly when hemorrhages are large (Martin et al., 1976; Johnsen et al., 2005; Limperopoulos et al., 2007, 2014; Zayek et al., 2012). Reported rates of motor delay ascertained by standardized developmental measures range from 15% to 100% depending on the study (Limperopoulos et al., 2007; Zayek et al., 2012; Steggerda et al., 2013), though it is unclear what proportion of those with delay were ultimately diagnosed with disability.
Cerebellar Hemorrhage
2018, Volpe's Neurology of the NewbornSystemic inflammation combined with neonatal cerebellar haemorrhage aggravates long-term structural and functional outcomes in a mouse model
2017, Brain, Behavior, and ImmunityCitation Excerpt :Cerebellar growth is highly vulnerable during the third trimester of pregnancy and could be affected by diverse direct insults leading to cerebellar growth failure and atrophy (Johnsen et al., 2002; Limperopoulos, 2005a; Mercuri et al., 1997). Cerebellar haemorrhage (CBH) affects from 3 to 37% of infants born extremely preterm (Dyet et al., 2006; Hou et al., 2011; Martin et al., 1976; Müller et al., 0000; O’Shea et al., 2008; Sehgal et al., 2009; Steggerda et al., 2009; Zayek et al., 2011) and presents mainly as a unilateral intraparenchymal focal or multifocal haemorrhage in 70% of the cases (Limperopoulos, 2005b,a). Currently, no accurate translational animal model reproduces the most prevalent type of CBH in the developing premature brain.