Brief clinical and laboratory observationMethadone withdrawal in newborn infants
References (6)
- et al.
Absence of respiratory distress syndrome in premature infants of heroin addicted mothers
Lancet
(1971) - et al.
The course of the heroin withdrawal syndrome in newborn infants treated with phenobarbital or chlorpromazine
J. Pediatr.
(1969) - et al.
A medical treatment for diocetylmorphine (heroin) addiction
J. A. M. A.
(1965)
Cited by (72)
Research gaps on methadone harms and comparative harms: Findings from a review of the evidence for an American Pain Society and College on Problems of drug dependence clinical practice guideline
2014, Journal of PainCitation Excerpt :Effects of methadone on neonatal outcomes are difficult to assess because of confounding effects related to selection of the control group (eg, ongoing heroin use or drug-free controls), failure of most studies to adjust for potential confounders, and inconsistent results. Rates of neonatal abstinence syndrome diagnosis in infants of women prescribed methadone were generally 75% or more,28,57,63,64,74,86,96,97,103,104,133 though rates of treatment for neonatal abstinence syndrome were low in some studies.6,39,63,72,109,133 Evidence regarding the comparative incidence, severity, or time course of neonatal abstinence syndrome due to methadone compared to buprenorphine were inconsistent in 4 RCTs and 4 cohort studies, preventing strong conclusions.6,10,46,60,61,63,71,72
Medication assisted drug treatment and child well-being
2007, Children and Youth Services ReviewFetal response to maternal methadone administration
2005, American Journal of Obstetrics and GynecologyUse of buprenorphine in pregnancy: Patient management and effects on the neonate
2003, Drug and Alcohol DependenceThe role of opioid receptors in morphine withdrawal in the infant rat
2000, Developmental Brain Research
- *
Address: 530 Lenox Ave., New York, N. Y. 10037.