PUBLIC HEALTHPsychological and social consequences of community carrier screening programme for cystic fibrosis
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Cited by (88)
To know or not to know, disclosure of a newborn carrier screening test result for cystic fibrosis
2013, European Journal of Medical GeneticsCitation Excerpt :Finally, other previously born children in the family still asymptomatic may be discovered by sweat testing or DNA analysis [5]. However, some health professionals consider detection of healthy carriers undesirable because it may cause confusion and anxiety for the parents, and therefore lead to problems in the child–parent relationship and/or early stigmatization [6]. Therefore, carrier identification can be judged a major problem when implementing community-based screening.
Three-month follow-up of Western and non-Western participants in a study on preconceptional ancestry-based carrier couple screening for cystic fibrosis and hemoglobinopathies in the Netherlands
2008, Genetics in MedicineCitation Excerpt :Some CF carriers even perceived themselves as less healthy,10,14 whereas others falsely believed that they were only likely to be carriers.10,11,14 Many couples in which only one partner had been identified as a carrier were unaware of their residual risk of having an affected child—a risk because of the limited sensitivity of the DNA testing.17,21,22 Correspondingly, it was found among those who tested negative, that they falsely believed that they were definitely not carriers,11,14 although they had been informed that the test-sensitivity was <100%.
Preconception risk assessment for thalassaemia, sickle cell disease, cystic fibrosis and Tay-Sachs disease
2021, Cochrane Database of Systematic ReviewsPreconception risk assessment for thalassaemia, sickle cell disease, cystic fibrosis and Tay-Sachs disease
2018, Cochrane Database of Systematic Reviews