Fetus-Placenta-NewbornNucleated red blood cells: A marker for fetal asphyxia?
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Cited by (95)
Persistent increase in red cell size distribution width after acute diseases: A biomarker of hypoxemia?
2015, Clinica Chimica ActaNucleated red blood cell counts: An early predictor of brain injury and 2-year outcome in neonates with hypoxic-ischemic encephalopathy in the era of cooling-based treatment
2014, Brain and DevelopmentCitation Excerpt :Thus, there is a need to establish a simple, quick, and accurate method to predict the occurrence of HIE and brain damage before initiating HT [5,6]. The nucleated red blood cell (NRBC) count in umbilical and peripheral blood after birth has been reported to be a marker of perinatal asphyxia [7–10]. This is based on the fact that hypoxic events induce a rapid fetal compensatory response in the form of accelerated erythropoiesis, resulting in the influx of immature red blood cells into fetal blood circulation [11].
Understanding cardiotocographic patterns associated with intrapartum fetal hypoxia and neurologic injury
2013, Best Practice and Research: Clinical Obstetrics and GynaecologyCitation Excerpt :In the absence of acidaemia, the CTG will show absence of decelerations despite the brain damage. At birth, these babies have raised nucleated red blood cells,37,38 prolonged nucleated red blood cells clearance times,37,39 suggestive of antecedent hypoxic insult, multi-organ system dysfunction,39 delayed onset of seizures,40 cortical brain injuries,7 old meconium, meconium aspiration syndrome, and pulmonary hypertension.6 Severely growth restricted babies are disproportionately represented in this group.
Nucleated Red Blood Cells and early EEG: Predicting Sarnat stage and two year outcome
2011, Early Human DevelopmentCitation Excerpt :In addition we found significantly higher NRBC counts in infants with abnormal outcome at 2 years. In a retrospective review, Phelan demonstrated that NRBC counts were raised in those with neurological impairment post asphyxia, compared to non-asphyxiated healthy controls [8]. Since then, Buonocore et al. found prospectively that NRBC counts were significantly higher in infants with abnormal cerebral Doppler ultrasonography at 48–72 h, with abnormal cranial US at 6 months, and those with abnormal neurological status at 3 years [13].