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Case Series of Infants Presenting with End Stage Retinopathy of Prematurity to Two Tertiary Eye Care Facilities in Mexico: Underlying Reasons for Late Presentation

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Abstract

To describe the characteristics of infants with bilateral Stage 4b or 5 ROP (i.e. with subtotal or total retinal detachment) who presented to eye departments in two major cities in Mexico, to identify reasons why they may have become blind in order to recommend how programs could be improved. A large case-series of infants with Stage 4b or 5 ROP in both eyes confirmed by ultrasound who attended the ROP Clinic, Hospital Civil de Guadalajara from September 2010 to November 2012, and the Department of Ophthalmology, Hospital Infantil de Mexico Federico Gomez from December 2011 to December 2012 were identified from the diagnostic databases of each hospital. Mothers of infants in Guadalajara had a telephone interview. 89/94 eligible infants were included in the study, 48 in Guadalajara and 41 in Mexico City. Cases came from 22 of the 32 states in Mexico. Half of the infants attending Guadalajara 24/48 (50 %) had been cared for in NICUs without ROP screening programs and were not examined. Among the 24 infants cared for in NICUs with ROP programs, 7/24 (29.1 %) mothers reported that their infant had not been examined while in the NICU, and a further 9/24 (37.5 %) were either not referred for screening after discharge or they did not attend. Two infants had failed laser treatment. Strategies and resources to prevent end stage ROP have not been firmly established in Mexico. There is an urgent need to expand the coverage and quality of ROP programs, to ensure that existing screening guidelines are better adhered to, and to improve communication with parents.

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Authors and Affiliations

  1. Clinic of Retinopathy of Prematurity and Blindness Prevention, Hospital Civil de Guadalajara, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Mexico, Boulevard Puerta de Hierro 5150, C.P. 45116, Zapopan, Jalisco, Mexico

    Luz C. Zepeda-Romero

  2. Clinic of Retinopathy of Prematurity and Blindness Prevention, Hospital Civil de Guadalajara, Universidad Guadalajara LAMAR, Guadalajara, Mexico

    Alonso Meza-Anguiano

  3. Division of Education on Health, UMAE Hospital de Pediatría, Centro Medico Nacional de Occidente, Instituto Mexicano del Seguro Social, Guadalajara, Mexico

    Juan C. Barrera-de León

  4. Centro Universitario de Ciencias de la Salud, Hospital Civil de Guadalajara, Universidad de Guadalajara, Guadalajara, Mexico

    Eusebio Angulo-Castellanos & José A. Gutiérrez-Padilla

  5. Department of Ophthalmology, Hospital Infantil de Mexico Federico Gomez, Distrito Federal, Mexico

    Marco A. Ramirez-Ortiz

  6. International Centre for Eye Health, Clinical Research Unit, London School of Hygiene and Tropical Medicine, London, UK

    Clare E. Gilbert

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  1. Luz C. Zepeda-Romero
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Correspondence to Luz C. Zepeda-Romero.

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Zepeda-Romero, L.C., Meza-Anguiano, A., Barrera-de León, J.C. et al. Case Series of Infants Presenting with End Stage Retinopathy of Prematurity to Two Tertiary Eye Care Facilities in Mexico: Underlying Reasons for Late Presentation. Matern Child Health J 19, 1417–1425 (2015). https://doi.org/10.1007/s10995-014-1648-z

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  • DOI: https://doi.org/10.1007/s10995-014-1648-z

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