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Accuracy and precision of a new, portable, handheld blood gas analyzer, the IRMA®

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Abstract

Objective. The accuracy and precision of the new IRMA® (Immediate Response Mobile Analysis System, Diametrics, Inc.®, St. Paul, MN) handheld blood gas analyzer was compared with that of two benchtop blood gas analyzers. The IRMA consists of a notebook-sized machine and disposable cartridges, each containing a pH, a CO2 and an O2 electrode, and provides bedside (point-of-care) blood gas analysis.Methods. A total of 172 samples (arterial and mined venous) were obtained from 25 informed, consenting patients undergoing cardiopulmonary bypass. The pH, PCO2 and PO2 of each sample was determined on four blood gas analyzers: NOVA Statlabs Profile 5 (NOVA Biomedical, Waltham, MA), the ABL-50 (Radiometer, West Lake, OH), and two IRMA machines. Linear regression and bias ± precision were determined, comparing each of the analyzers with the NOVA.Results. All three machines showed a similar, high degree of correlation with the NOVA for pH, PCO2, and PO2. The bias and precision of the IRMA machines compared with the NOVA was similar to that of the ABL compared with the NOVA for pH (NOVA:ABL −0.005 ± 0.011; NOVA: IRMA 1 = 0.0026 ± 0.025; NOVA: IRMA 2 = 0.0021 ± 0.025), for PCO2 (NOVA:ABL = −1.4 ± 1.3 mmHg; NOVA: IRMA 1 = −1.3 ± 1.9 mmHg; NOVA: IRMA 2 = −1.2 ± 2.1 mmHg) and PO2 (NOVA:ABL = 3.6 ± 21.1 mmHg; NOVA: IRMA 1 = 3.4 = 19.9 mmHg; NOVA: IRMA 2 = 6.3 ± 20.9 mmHg). The bias found for pH, PCO2, and PO2 was not affected by extremes of temperature (range 25.5–40°C) or hematocrit (range 11–44%) for any machine.Conclusions. The new technology incorporated in the IRMA blood gas analyzer provides results with an accuracy that is similar to that of benchtop analyzers, but with all of the advantages of point-of-care analysis.

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References

  1. Hamilton RD, Crockett RJ, Alpers JH. Arterial blood gas analysis: Potential errors due to the addition of heparin. Anaesth Intensive Care 1978; 6: 251–255.

    PubMed  CAS  Google Scholar 

  2. Biswas CK, Ramos JM, Agroyannis B, Kerr DN. Blood gas analysis: Effect of air bubbles in syringe and delay in estimation. Br Med J 1982; 284 (6320): 923–927.

    Article  CAS  Google Scholar 

  3. Ishikawa S, Former A, Borst C, Segal MS. The effects of air bubbles and time delay on blood gas analysis. Ann Allergy 1974; 33 (2): 72–77.

    PubMed  CAS  Google Scholar 

  4. McKane MH, Southorn PA, Santrach PJ, Burritt MF, Plevak DJ. Sending blood gas specimens through pressurized transport tube systems exaggerates the error in oxygen tension measurements created by the presence of air bubbles. Anesth Analg 1995; 81: 179–182.

    Article  PubMed  CAS  Google Scholar 

  5. Bland JM, Altman DG. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1986; 1 (8476): 307–310.

    PubMed  CAS  Google Scholar 

  6. Cartwright K, Turner H. Safety aspects of outstationed laboratory equipment [see comments]. J Hosp Infect 1992; 20 (4): 225–231.

    Article  PubMed  CAS  Google Scholar 

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Wahr, J.A., Lau, W., Tremper, K.K. et al. Accuracy and precision of a new, portable, handheld blood gas analyzer, the IRMA®. J Clin Monitor Comput 12, 317–324 (1996). https://doi.org/10.1007/BF02221753

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  • DOI: https://doi.org/10.1007/BF02221753

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