Abstract
Echogenic stripes in the basal ganglia were identified sonographically in a 4-month-old infant with human immunodeficiency virus (HIV) infection. This lenticulostriate arteriopathy correlated well with histologically identified early alterations of HIV encephalopathy in children. At 3 years and 5 months, CT examination performed after three seizures showed calcification in the area of the sonographically affected arteries but no sings of progressive encephalopathy. The child's mental and motor development have remained normal until now. Cerebral sonography performed in early infancy may allow identification of HIV encephalopathy even before its clinical manifestation.
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References
European Collaborative Study (1991) Children born to women with HIV-1 infection: natural history and risk of transmission. Lancet 337: 253–260
Epstein LG, Sharer LR, Oleske JM, Connor EM, Goudsmit J, Bagdon L, Robert-Guroff M, Koenigsberger MR (1986) Neurologic manifestations of human immunodeficiency virus infection in children. Pediatrics 78: 678–687
Belman AL, Lantos G, Horoupian D, Novick BE, Ultmann MH, Dickson DW, Rubinstein A (1986) AIDS: calcification of the basal ganglia in infants and children. Neurology 36: 1192–1199
Sica GT, Norton KI (1990) Intracranial human immunodeficiency virus infection in an infant: sonographic findings. Pediatr Radiol 21: 64–65
Bode H, Rudin C, Bubl R (1991) Noncalcific vasculopathy in the basal ganglia. Klin Padiatr 203: 350–353
Ries M, Deeg KH (1994) Diagnose der nichtkalzifizierenden Vaskulopathie im Bereich der Basalganglien mit Hilfe der farbkodierten Doppler-Sonographie. Monatsschr Kinderheilkd 142: 29–32
Morant J, Ruppauner H (eds) (1993) Arzneimittelkompendium der Schweiz 1994 Documed, Basel
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Bode, H., Rudin, C. Calcifying arteriopathy in the basal ganglia in human immunodeficiency virus infection. Pediatr Radiol 25, 72–73 (1995). https://doi.org/10.1007/BF02020858
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DOI: https://doi.org/10.1007/BF02020858