Summary
Forty-eight preterm infants (mean birthweight 1.0±0.3 kg; mean gestational age 28±3 weeks) underwent serial echocardiograms and physical examinations in order to determine the correlation between color Doppler flow mapping (CDFM) results and physical findings of a patent ductus arteriosus (PDA), the predictive value of early CDFM as an indicator of subsequent requirement for treatment of a PDA, and to determine the direction and duration of ductal shunting and the rate of ductal closure and opening. CDFM analysis and cardiac physical examination of left-to-right ductal shunting were usually concordant in infants with a large PDA shunt, the most reliable physical finding being increased precordial activity. CDFM studies on day 2 or 3 of postnatal life had prognostic value with regard to subsequent need for closing the PDA. Additional findings included the absence of right-to-left PDA shunting in infants <1 kg and <28 weeks gestation and the absence of ductal reopening in infants in whom it had closed spontaneously. After complete PDA closure using indomethacin, subsequent ductal reopening is uncommon, except in infants <25 weeks gestation and <700 g bodyweight.
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Roberson, D.A., Silverman, N.H. Color Doppler flow mapping of the patent ductus arteriosus in very low birthweight neonates: Echocardiographic and clinical findings. Pediatr Cardiol 15, 219–224 (1994). https://doi.org/10.1007/BF00795730
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DOI: https://doi.org/10.1007/BF00795730