ORs for the risk of MDI<85 determined using multiple logistic regression analysis
| OR (95% CI) | p Value | |
|---|---|---|
| Gestational age | 0.778 (0.572 to 1.057) | 0.11 |
| Birth weight | 1.000 (0.997 to 1.003) | 0.79 |
| SGA (yes or no)* | 2.995 (0.980 to 9.151) | 0.054 |
| Moderate or severe BPD† | 2.146 (1.047 to 4.399) | 0.037 |
| IVH grade 1–2 | 1.517 (0.730 to 3.153) | 0.26 |
| IVH grade 3–4 | 1.515 (0.619 to 3.705) | 0.36 |
| PVL (yes or no) | 3.854 (1.154 to 12.871) | 0.028 |
| NEC | 3.881 (1.039 to 14.502) | 0.044 |
| Hydrocortisone given (yes or no) | 1.198 (0.588 to 2.438) | 0.62 |
All factors listed in this table were shown to be statistically significant using univariate regression analysis.
Adjusted p values from multiple logistic regression model.
*SGA defined as birth weight <10th percentile.
†BPD according to the trial definition, corresponding to moderate or severe BPD according to the consensus definition.32
The c-statistic for this model is 0.73.
BPD, bronchopulmonary dysplasia; IVH, intraventricular haemorrhage; MDI, Mental Developmental Index; NEC, necrotising enterocolitis; PVL, periventricular leukomalacia; SGA, small for gestational age.