High target (n=130) | Control (n=135) | p Value | |
---|---|---|---|
MDI* | 82 (49–120, 122) | 84 (49–118, 127) | 0.79 |
MDI<85 | 67/122 (55) | 64/127 (50) | 0.47 |
MDI<70 | 37/122 (30) | 41/127 (32) | 0.74 |
PDI* | 84 (49–114, 109) | 84 (49–114, 117) | 0.73 |
PDI<85 | 56/109 (51) | 62/117 (53) | 0.81 |
PDI<70 | 36/109 (33) | 39/117 (33) | 0.96 |
Total mortality by follow-up | 27/179 (15) | 21/180 (12) | 0.34 |
Hearing impairment | 8/127 (6) | 5/132 (4) | 0.35 |
Visual impairment | 24/127 (19) | 26/133 (20) | 0.89 |
NDI (MDI<70 or PDI<70 or hearing impairment or visual impairment) | 58/115 (50) | 57/118 (48) | 0.75 |
NDI or death | 85/142 (60) | 78/139 (56) | 0.52 |
GMFCS level 0 | 64 (49) | 69 (51) | 0.23 |
GMFCS level 1 | 40 (31) | 49 (36) | |
GMFCS level 2 | 13 (10) | 4 (3) | |
GMFCS level 3 | 4 (3) | 6 (4) | |
GMFCS level 4 | 7 (5) | 6 (4) | |
GMFCS level 5 | 2 (2) | 1 (1) | |
CDI score* | 22 (1–50, 95) | 23 (1–58, 88) | 0.56 |
Percentiles for CDI scores† | 5 (<2—>90) | 10 (<2—>90) | |
Weight at follow-up (kg)* | 10.5 (5·6–15.0, 122) | 10.5 (7.0–17.2, 132) | 0.84 |
Height at follow-up (cm)* | 84 (66–96, 121) | 85 (70–102, 132) | 0.40 |
Head circumference (cm)* | 47 (40–52, 123) | 47 (43–50, 130) | 0.54 |
Corrected age at follow-up (months)* | 24 (18–28) | 24 (19–31) | 0.46 |
Unless otherwise specified, data are given as number of infants (%), χ2 test.
*Median (minimum–maximum, n), Mann-Whitney U-test.
†According to the standard sample: median (minimum–maximum).
CDI, Child Development Inventory; GMFCS, Gross Motor Function Classification System; MDI, Mental Developmental Index; PDI, Psychomotor Developmental Index.