BSIDIII composite scale scores across the developmental domains in each of the study groups
| Outcome | SGA (n=51) | TGA (n=51) | STGA (n=13) | AGA (n=189) |
|---|---|---|---|---|
| Cognitive score | 95 (90–100) | 95 (90–97.5) | 90 (85–95) | 95 (90–100) |
| p Value* | 0.15 | 0.036 | 0.005 | – |
| Hedges’ g effect size | 0.20 | 0.375 | 0.79 | – |
| Language score | 109 (97–117) | 100 (94–109) | 99 (88–109) | 109 (100–115) |
| p Value | 0.57 | 0.024 | 0.129 | – |
| Hedges’ g effect size | 0.06 | 0.35 | 0.57 | – |
| Motor score | 103 (94–110) | 100 (91–97) | 96 (90–103) | 103 (97–110) |
| p Value | 0.95 | 0.051 | 0.043 | – |
| Hedges’ g effect size | 0.08 | 0.41 | 0.71 | – |
| Crude OR (95% CI) | 1.37 (0.62 to 3.00) | 1.73 (0.8 to 3.72) | 4.58 (1.44 to 14.62) | – |
| p Value | 0.44 | 0.16 | 0.01 | |
| Adjusted OR (95% CI) | 1.36 (0.60 to 3.18) | 1.78 (0.80 to 3.99) | 5.00 (1.46 to 17.13) | – |
| p Value | 0.45 | 0.16 | 0.01 | |
| Age at assessment | 26.65 (1.6) | 26.6 (1.5) | 26.5 (1.7) | 26.21 (3.1) |
| p Value | 0.16 | 0.21 | 0.54 |
Data are presented as the median (IQR).
*p Values calculated using Mann-Whitney U test to compare group scores with AGA reference group. Crude OR, unadjusted OR calculated for the risk of abnormal score (<85) in any of the measured domains compared with the reference AGA group. Adjusted OR, adjusted for sex, maternal years of schooling, socioeconomic index and smoking status during pregnancy.
AGA, appropriate-for-gestational age; BSIDIII, Bayley Scales of Infant and Toddler Development Version III; SGA, small-for-gestational age; STGA, small- and thin-for-gestational age; TGA, thin-for-gestational age.