Table 2

Educational attainment lower than level 4* in English, mathematics and science at Key Stage 2 by ORACLE treatment groups

ErythromycinNo erythromycinCo-amoxiclavNo co-amoxiclav
Preterm rupture of membranes
1512152815231517
English (n)
 <Level 4 (%)350 (25.6)342 (24.6)326 (23.5)366 (26.7)
 OR (95% CI)†1.05 (0.89 to 1.26) 0.85 (0.71 to 1.01) 
Mathematics (n)
 <Level 4 (%)377 (27.7)364 (26.1)366 (26.4)375 (27.4)
 OR (95% CI)1.08 (0.91 to 1.29)0.95 (0.80 to 1.13)
Science (n)
 <Level 4 (%)126 (15.1)129 (15.3)119 (14.1)136 (16.3)
 OR (95% CI)0.98 (0.75 to 1.30) 0.84 (0.64 to 1.11) 
Spontaneous preterm labour
1550149714981549
English (n)
 <Level 4 (%)352 (24.8)335 (24.8)321 (23.8)366 (25.8)
 OR (95% CI)1.00 (0.84 to 1.19) 0.90 (0.75 to 1.07) 
Mathematics (n)
 <Level 4 (%)394 (27.7)360 (26.6)354 (26.1)400 (28.2)
 OR (95% CI)1.06 (0.89 to 1.25) 0.90 (0.76 to 1.07) 
Science (n)
 <Level 4 (%)130 (15.4)117 (14.5)105 (13.2)142 (16.7)
 OR (95% CI)1.07 (0.81 to 1.42) 0.76 (0.57 to 1.01) 
  • *Level 4 is the minimum standard which children are expected to achieve.

  • †OR, Mantel–Haenszel ORs (95% CIs).