Duration of mechanical ventilation in the intervention groups for the included studies
| Study | Unit of measurement | LISA group | Control group | p Value |
|---|---|---|---|---|
| Göpel et al27 | Days, median (IQR) | 0 (0–3) | 2 (0–5) | <0.0001 |
| Kanmaz et al28 | Hours, median (range) | 35.6 (0–756) | 64.1 (0–489) | 0.006 |
| Mirnia et al29 | Hours, mean (SEM) | 25.18±8.7 | 13.44±3.7 | 0.2 |
| Bao et al30 | Days, mean (SD) | 6.7 (3.5) | 7.4 (4.3) | 0.4 |
| Mohammadizadeh et al31 | Hours, mean (SD) | 36±16.9 | 144±109.9 | 0.2 |
| Kribs et al32 | Days, median (IQR) | 5 (0–17) | 7 (2.5–19.5) | 0.03 |
LISA, less invasive surfactant administration.