SpO2 80–92% | SpO2 85–96% | p Value | |
---|---|---|---|
Cumulative cerebral StO2 desaturation score* | 27384 (15825–37396) | 18103 (6964–32946) | 0.011 |
Number of events† | 29.1 (±15.3) | 21.1 (±11.4) | 0.001 |
Number of bradycardias only‡ | 0 (0–10) | 0 (0–14) | 0.469 |
Number of SpO2 desaturations only* | 14.5 (9.5–26.0) | 10.0 (4.5–19.5) | 0.002 |
Number of combined (SpO2 and bradycardia) events* | 9.0 (3.0–19.3) | 6.5 (3.3–12.3) | 0.094 |
Cumulative duration of events (min)† | 119.6 (±62.8) | 93.6 (±67.8) | 0.016 |
Mean duration of single event (s)* | 253 (201–318) | 239 (187–290) | 0.782 |
Mean severity (difference baseline to mean cerebral StO2 during event) of single event (%)† | 6.8 (±2.9) | 6.8 (±2.8) | 0.825 |
Mean severity (difference baseline to cerebral StO2 nadir) of single event (%)† | 14.2 (±6.3) | 13.9 (±5.8) | 0.630 |
Cerebral StO2 desaturation score per event* | 1042 (571–1528) | 869 (448–1715) | 0.86 |
Median SpO2 (%)† | 89.2 (±2.6) | 91.1 (±1.5) | 0.004 |
25th percentile SpO2 (%)† | 83.9 (±2.5) | 85.9 (±2.7) | 0.003 |
75th percentile SpO2 (%)† | 92.6 (±2.5) | 93.9 (±1.1) | 0.017 |
SpO2 <80% (min)* | 57.2 (40.6–77.0) | 34.0 (16.0–45.6) | 0.006 |
SpO2 <75% (min)* | 22.7 (14.2–35.6) | 13.9 (8.0–21.8) | 0.018 |
SpO2 ≥97% (min)* | 13.2 (5.9–32.0) | 19.1 (5.6–54.5) | 0.16 |
SpO2 ≥99% (min)* | 2.1 (0.2–5.7) | 1.3 (0.2–6.5) | 1.0 |
SpO2 within target range (min)† | 284.1 (±72.6) | 355.7 (±42.8) | <0.001 |
SpO2 below target range (min)† | 57.3 (±24.8) | 92.6 (±36.2) | <0.001 |
SpO2 above target range (min)† | 137.0 (±76.7) | 30.0 (±29.1) | <0.001 |
Median cerebral StO2 (%)† | 70.2 (±7.3) | 70.3 (±7.2) | 0.960 |
Cerebral StO2 <60% (min)* | 25.2 (3.9–129.5) | 11.2 (1.1–145.9) | 0.30 |
Cerebral StO2 <55% (min)* | 4.9 (0.1–70.8) | 1.5 (0.0–36.2) | 0.39 |
Cerebral StO2 within 10th–90th percentile (min)† | 354.9 (±95.0) | 357.3 (±95.1) | 0.878 |
Cerebral StO2 >81.0 (90th percentile) (min)* | 27.8 (0.1–56.3) | 17.6 (1.1–69.1) | 0.463 |
Cerebral StO2 >84.5 (97th percentile) (min)* | 6.6 (0.0–20.3) | 3.9 (0.0–17.9) | 0.102 |
Median cerebral FTOE (%)† | 20.4 (±8.0) | 21.9 (±8.0) | 0.051 |
Median HbT† | 54.5 (±16.6) | 56.8 (±15.1) | 0.180 |
Median HbD† | 22.4 (±11.4) | 23.2 (±11.4) | 0.330 |
*Median (IQR).
†Mean (SD).
‡Median (Range).
Cerebral StO2, cerebral tissue oxygen saturation; FTOE, fractional tissue oxygen extraction; HbD, haemoglobin difference; HbT, total haemoglobin concentration; SpO2, pulsoximetric oxygen saturation.