Intakes of energy and macronutrients and associations with retinopathy of prematurity (stages 3–5) during the first 4 weeks of life (n=498)
| Energy | Protein | Carbohydrates | Fat | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Kcal (SD) | OR† | 95% CI | Gram (SD) | OR‡ | 95% CI | Gram (SD) | OR‡ | 95% CI | Gram (SD) | OR‡ | 95% CI | |
| Week 1 | 66 (10) | 0.75** | 0.61 to 0.92 | 2.2 (0.6) | 1.08 | 0.78 to 1.50 | 9.1 (1.3) | 0.87 | 0.75 to 1.01 | 2.2 (0.8) | 0.75* | 0.58 to 0.97 |
| Week 2 | 102 (17) | 0.80** | 0.71 to 0.92 | 3.0 (0.5) | 0.90 | 0.62 to 1.30 | 11.3 (1.4) | 0.86* | 0.74 to 0.98 | 4.7 (1.5) | 0.83** | 0.72 to 0.96 |
| Week 3 | 116 (21) | 0.82*** | 0.74 to 0.91 | 3.3 (0.6) | 0.88 | 0.63 to 1.23 | 12.0 (1.6) | 0.89 | 0.78 to 1.01 | 5.8 (1.8) | 0.82** | 0.73 to 0.92 |
| Week 4 | 124 (21) | 0.86** | 0.78 to 0.95 | 3.4 (0.7) | 0.71* | 0.52 to 0.97 | 12.4 (1.7) | 0.86* | 0.76 to 0.98 | 6.4 (1.9) | 0.88* | 0.79 to 0.98 |
| Weeks 1–4 | 102 (14) | 0.72*** | 0.62 to 0.84 | 3.0 (0.4) | 0.75 | 0.47 to 1.21 | 11.2 (1.1) | 0.76** | 0.63 to 0.92 | 4.8 (1.2) | 0.75** | 0.63 to 0.89 |
Logistic regression analysis.
Adjusted for gestational age and birth weight.
*p<0.05, **p<0.01, ***p<0.001.
†Energy: 10 kcal/kg/day increment.
‡Protein, carbohydrates and fat: 1 g/kg/day increment.