Secondary study variables (n=19)
| Mode of ventilation | p Value* | SNIPPV (p)† | ||||
|---|---|---|---|---|---|---|
| SNIPPV | NIPPV | NCPAP | vs NIPPV | vs NCPAP | ||
| Central apnoeas (≥10 s) per hour | 2.4 (1–3.6) | 6.3 (2.8–17) | 5.4 (3.1–12) | 0.002 | 0.001 | 0.001 |
| HR (bpm) | 156 (150–161) | 158 (149–162) | 159 (154–163) | <0.001 | 0.481 | 0.111 |
| Baseline RR (bpm) | 57 (50–64) | 54 (49–60) | 53 (47–57) | 0.058 | 0.440 | 0.663 |
| FiO2 | 0.22 (0.21–0.25) | 0.21 (0.21–0.26) | 0.22 (0.21–0.26) | 0.000 | 0.607 | 0.814 |
| SpO2 (%) | 91 (90–96) | 91 (90–93) | 91 (90–97) | 0.003 | 0.061 | 0.185 |
| PtcO2 (mm Hg) | 58 (45–71) | 54 (49–75) | 53 (48–68) | 0.020 | 1.887 | 1.015 |
| PtcCO2 (mm Hg) | 49 (46–52) | 52 (43–58) | 49 (42–55) | 0.018 | 1.849 | 0.787 |
Data are expressed as median (IQR).
*Friedman's test.
†After Bonferroni adjustment.
HR, heart rate; NCPAP, nasal continuous positive airway pressure; NIPPV, nasal intermittent positive pressure ventilation; RR, respiratory rate; SNIPPV, synchronised NIPPV.