Study | BW/GA | ROP | Age | Refractive errors |
---|---|---|---|---|
EXPRESS25 | <27 weeks | 73.7% (20.4% treated) | 30 months | 25.6%—all |
CRYO-ROP Study26 | <1251 g | All reached threshold (82.5% bilateral) | 3.5 years | Moderate myopia (≥2 D to <6 D):
|
ETROP27 | <1251 g | High-risk prethreshold | 6 years | Astigmatism ≥52% in all treated eyes High astigmatism ≥23% in all treated eyes |
ETROP23 | Myopia ≥65% in all treated eyes High myopia≥35% in all treated eyes | |||
Larsson and Holmström20 | <1501 g | 39% | 10 years | Moderate myopia 3.8% Moderate hypermetropia 4.2% Astigmatism 21% |
O'Connor et al22 | <1701 g | 50% | 10–12 years | Mild myopia 15.2% Moderate myopia 3.8% Moderate hypermetropia 6.6% |
Refractive errors are defined (unless otherwise stated) as mild myopia <3.0 dioptre sphere, moderate ≥3 dioptre sphere, high myopia >5.0 dioptre sphere, moderate hypermetropia ≥3.0 dioptre sphere, astigmatism ≥1.00 dioptres and high astigmatism ≥2.00 dioptres.
BW, birth weight; D, dioptre; GA, gestational age.