Independent | Pearson χ2 or ANOVA* statistic | p Value |
---|---|---|
Seizures (yes/no) | 12.86 | <0.001 |
Seizure burden (high or low) | 18.25 | <0.001 |
Burst suppression, continuous low voltage or flat trace in first 24 h | 15.31 | <0.001 |
Burst suppression, continuous low voltage or flat trace at 48 h age | 13.89 | 0.001 |
Cord or first pH within 1 h | *F=1.15 | 0.29 |
Cord or first base excess within 1 h | *F=2.29 | 0.09 |
Apgar at 10 min | *F=15.91 | <0.001 |
Use of anticonvulsants | 4.52 | 0.10 |
Infants needing more than one anticonvulsant compared with those needing one | 6.79 | 0.009 |
Age at MRI | *F=1.29 | 0.22 |
Multivariate regression model assessing the effect of factors significant in above bivariate analyses on MRI outcomes | ||||
---|---|---|---|---|
Factor | OR | 95% CI | p Value | |
Lower | Upper | |||
Seizure burden | 5.00 | 1.47 | 17.05 | 0.01 |
Apgar at 10 min | 0.80 | 0.59 | 1.10 | 0.18 |
Abnormal aEEG background in first 24 h | 2.30 | 0.50 | 10.51 | 0.28 |
aEEG background at 48 h | 2.55 | 0.48 | 13.54 | 0.27 |
*ANOVA, analysis of variance.